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Pharma and Biotech
Processing a wide range of pharmaceutical and biotech products

Flexible and efficient sterile filling with MultiUse systems

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As a pharmaceutical manufacturer, you process a wide range of active ingredients and packaging materials, from liquid and viscous to high-potency, in syringes, vials or cartridges. We have launched OPTIMA MultiUse to give you total flexibility for all your filling needs. The system profile covers all your applications from product and process development in R&D to clinical trials and commercial production - quickly and economically.

Filling flexibility – with MultiUse systems from OPTIMA

The pharmaceuticals market is diverse and fast-paced. Your production will stay on track with MultiUse systems from Optima Pharma: You can process different batch sizes, packaging and containers flexibly and cost-effectively. The system covers all performance requirements. It is designed to handle different product characteristics including liquid, viscous and freeze-dried products.


As a turnkey partner we integrate all process steps upon request, including isolators and freeze dryers. And with our CSPE process, we get your MultiUse system up and running in record time. CSPE means „Comprehensive Scientific Process Engineering“ and it speeds up your system's development and assembly. Select total flexibility for your sterile filling process - with the Optima MultiUse system.

Two containers filled with vials
Daniel Swissfillon
Daniel Kehl, Founder of swissfillon AG (Today: Ten 23 Health)

Optima is unrivaled when it comes to filling accuracy.

Daniel Kehl, Founder of swissfillon AG (Today: Ten 23 Health)
Score with OPTIMA pharma

Many reasons - one partner

Multiple packaging materials and containers
Filling syringes, vials, and cartridges into nests, trays, or bulk
Multiple products and active ingredients
You can process products from liquid to high viscosity and high potency
Maximum flexibility
Fast format changes, smart use of robotic systems
Minimal product loss
With smart technologies and in-process controls
Turnkey integration
Isolator, Ready-To-Use (RTU), Bulk and Lyo path are easily integrated
Absolute safety
Wide range of inspection and in-process-controls, no glass-to-glass-contact
Turnkey solution for maximum flexibility with one system
Turnkey solution for maximum flexibility with one system
Pharmaceutical MultiUse solution
1. Bulk path
2. Ready-To-Use path
3. Freeze-drying
4. Isolator
5. iFAT
Pharmaceutical MultiUse solution
1. Bulk path
Vials are brought to the dosing station via a bulk path

Vials that are not pre-sterilized arrive at the dosing station from the washing machine and the sterilization tunnel.

2. Ready-To-Use path
MultiUse plant

Pre-sterilized syringes, cartridges and vials in nests or trays arrive at the same filling station using the RTU path.

3. Freeze-drying
loading vials into a lyophilizator

Can be integrated and completed with a crimping station.

4. Isolator
Pharmaceutical machine view with isolator

Optional for all process steps.

5. iFAT
Five people in front of one machine

In order to perform the integrated Factory Acceptance Test, we assemble your entire system on our premises and perform cycle development. This ensures a safe production start in record time.

Many possibilities – one system

To ensure handling of all your products and containers using a MultiUse system, we focus on total flexibility, starting with the design stage: Multiple processing options mean maximum variability. The CSPE engineering process is particularly beneficial when combining processes that are different. See for yourself.

OPTIMA pharma | Experts for aseptic filling
Do you have questions or would you like to discuss your specific requirements with Optima's experts?
OPTIMA pharma | Experts for aseptic filling
OPTIMA pharma
+49 791 9495 - 0 customer.info@optima-packaging.comWrite e-mail
OPTIMA pharma | Experts for aseptic filling
OPTIMA pharma | Experts for aseptic filling
OPTIMA pharma
For R&D, clinical studies or commercial production
The MultiUse portfolio for your complete production life cycle

Cover all your applications and performance requirements with our MultiUse portfolio: From R&D product and process developments to clinical trial phases, for small, medium and large batch sizes. This means identical functions and validated processes scaled and applied for any application and output. Maximum flexibility, filling accuracy, and product yield always remain consistent.

MultiUse pharmaceutical solutionMultiUse pharmaceutical solution
MultiUse Lab System The laboratory solution

For trials, stabilization tests and more: The MultiUse version used in laboratories is designed to handle batch sizes up to 2,000 objects. This reduces the burden on your production equipment and simplifies  the development. The footprint remains minimal, even with an integrated isolator. Good to know: All processes developed can be transferred on a 1:1 basis to a larger MultiUse production line.

Turnkey SCADA solutionTurnkey SCADA solution
MultiUse systems for medium-sized outputs The all-round system

From filling in clinical trials to commercial production: With the MultiUse system for medium-sized outputs, you can flexibly meet all application requirements.

Pharma MultiUse solutionPharma MultiUse solution
The MultiUse system for high-output The high-performance solution

The dynamic pharma market is increasingly demanding high-performance multi-use solutions. The new generation of Optima systems meet this demand by combining ten-digit outputs with the signature concept of single processing with an output of up to 24,000 containers per hour.

Woman in front of a machine
Filling flexibility 100% packaging adaptability

Enjoy the unlimited flexibility of filling on a single system: You can process different packaging materials including syringes, vials or cartridges, in bulk or RTU ("Ready To Use") in tubs and trays, efficiently and virtually with no format parts. You also have maximum flexibility with processing paths. For instance, you can integrate parallel paths for RTU and bulk containers or for liquid and freeze-dried products.


Benefits:

The smart format part concept speeds-up size part changes
Various processing paths integrated into one machine
Two containers filled with vials
Filling flexibility 100% packaging adaptability

Enjoy the unlimited flexibility of filling on a single system: You can process different packaging materials including syringes, vials or cartridges, in bulk or RTU ("Ready To Use") in tubs and trays, efficiently and virtually with no format parts. You also have maximum flexibility with processing paths. For instance, you can integrate parallel paths for RTU and bulk containers or for liquid and freeze-dried products.


Benefits:

The smart format part concept speeds-up size part changes
Various processing paths integrated into one machine
Two containers filled with vials
Say goodbye to product loss

Technologies maximize your yield

Numerous technologies have been designed to maximize your product yield, from re-dosing and re-stoppering to re-capping and 100% process control.


Benefit:

Smart functions minimize product losses and save costs
Vial Filling
Say goodbye to product loss

Technologies maximize your yield

Numerous technologies have been designed to maximize your product yield, from re-dosing and re-stoppering to re-capping and 100% process control.


Benefit:

Smart functions minimize product losses and save costs
Vial Filling
Automated MultiUse systems

Robotic support

Robotics and kinematics interacting make your system more flexible and minimize operator involvement. One example is a fully-automated, format part-free linear transport. Treating your containers gently and preventing glass-to-glass contact. Robotic systems also take an active role in de-nesting and inserting containers.


Benefits:

No glass-to-glass-contact
Gentle material handling
Format part-free transport
Vials are inserted into a tray
Automated MultiUse systems

Robotic support

Robotics and kinematics interacting make your system more flexible and minimize operator involvement. One example is a fully-automated, format part-free linear transport. Treating your containers gently and preventing glass-to-glass contact. Robotic systems also take an active role in de-nesting and inserting containers.


Benefits:

No glass-to-glass-contact
Gentle material handling
Format part-free transport
Vials are inserted into a tray
In-process controls

Built-in protection

Safety is paramount for aseptic filling. Therefore, a large number of safety checks and inspection equipment monitors your production processes and products. For example, a sensor will check the syringe stopper height while a camera checks if the vials are correctly crimped.


Benefit:

Built-in controls ensure process and product safety
Detail of a pharmaceutical machine transporting vials
In-process controls

Built-in protection

Safety is paramount for aseptic filling. Therefore, a large number of safety checks and inspection equipment monitors your production processes and products. For example, a sensor will check the syringe stopper height while a camera checks if the vials are correctly crimped.


Benefit:

Built-in controls ensure process and product safety
Detail of a pharmaceutical machine transporting vials
Technologies for process safety

Playing it safe with digital technology

Digital technologies simplify the operation of your multi-purpose system and maximize your production process safety. For instance, augmented reality glasses can assist your operators. Select from digital tools for operation, production data management, maintenance and knowledge transfer.


Benefits:

Digital technologies increase safety and simplify operations
Choice of tools to meet the challenges of pharmaceutical production
Men servicing a machine with AR glasses
Technologies for process safety

Playing it safe with digital technology

Digital technologies simplify the operation of your multi-purpose system and maximize your production process safety. For instance, augmented reality glasses can assist your operators. Select from digital tools for operation, production data management, maintenance and knowledge transfer.


Benefits:

Digital technologies increase safety and simplify operations
Choice of tools to meet the challenges of pharmaceutical production
Men servicing a machine with AR glasses
Christophe Assourd, Head of Pharmaceutical Industrial Development at Servier, France

We were impressed by the project management and integrated design of the filling line, freeze dryer, and isolator for high-potency products, as well as the state-of-the-art technology of the flexible line and its '4.0 compliance'. In addition, the cooperation, in terms of technical communication, was also a determining factor for us.

Christophe Assourd, Head of Pharmaceutical Industrial Development at Servier, France
MultiUse for high potency drugs

Processing highly effective products

Optima's MultiUse systems can process even highly potent products. Machines and isolators are designed to handle these valuable pharmaceuticals. In addition, the systems ensure the safety of your personnel and your highly potent active ingredients during production.


Benefit:

Maximum safety for operators and pharmaceuticals
People in a laboratory
MultiUse for high potency drugs

Processing highly effective products

Optima's MultiUse systems can process even highly potent products. Machines and isolators are designed to handle these valuable pharmaceuticals. In addition, the systems ensure the safety of your personnel and your highly potent active ingredients during production.


Benefit:

Maximum safety for operators and pharmaceuticals
People in a laboratory
Bubble-free cartridge filling

100% bubble-free

The system's optimized technology fills cartridges 100% air bubble free using a multi-step filling process that works in tandem with vacuum stopper insertion. Stoppers, required for cartridges and used for pen injection, must be placed precisely.


Benefits:

Air bubble free filling of cartridges
Increased user safety
carpule filled
Bubble-free cartridge filling

100% bubble-free

The system's optimized technology fills cartridges 100% air bubble free using a multi-step filling process that works in tandem with vacuum stopper insertion. Stoppers, required for cartridges and used for pen injection, must be placed precisely.


Benefits:

Air bubble free filling of cartridges
Increased user safety
carpule filled
MultiUse success model: When are integrated portfolios used?

Optima MultiUse systems are used around the world - by start-up companies, CDMOs and pharmaceutical manufacturers. They are all impressed by the flexible, efficient system concept. Even expensive, special products can be filled in a range of different delivery formats. What will it take to convince you of the benefits of the integrated portfolio?

MultiUse plant
Tyvek removal of the RTU path of a MultiUse system
Vials are filled
MultiUse plant for filling highly specialized and expensive products
Machine grips a series of glass vials
Flexible use of robotics
Success stories with MultiUse systems – from OPTIMA and with OPTIMA

Real examples demonstrate the benefits of Optima's well-designed solutions. Dive into our success stories and become inspired.

OPTIMA pharma | Experts for aseptic filling
Do you have any questions about aseptic filling using MultiUse systems, or would you like to discuss your specific requirements?
OPTIMA pharma | Experts for aseptic filling
OPTIMA pharma
OPTIMA pharma | Experts for aseptic filling
OPTIMA pharma | Experts for aseptic filling
OPTIMA pharma
+49 791 9495 - 0 Write e-mail
Three Optima employees
Do you have questions or would you like to discuss your specific requirements with Optima's experts?
OPTIMA pharma | Experts for aseptic filling
OPTIMA pharma
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