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Lyophilization : platform based, modular and smart.


Customized and scalable turnkey freeze-drying solutions for the pharmaceutical and biotech industries

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Optima Pharma's modular systems for lyophilization (pharmaceutical freeze-drying) are precisely tailored to your production processes. Whatever the scale of your application, from clinical trials to commercial production, our freeze-dryers provide an adaptable turnkey solution for pharmaceutical lyophilization.

Our integrated approach makes us your go-to partner for lyophilizers, filling lines and isolators. We make seamlessly integrating lyophilization equipment into your pharmaceutical infrastructure a breeze. On top of this, our comprehensive turnkey project management takes the complexity out of your project. From consulting to standardized interfaces and documentation of the entire system, your personal Optima Pharma expert will always be at your side.

Our expertise in pharmaceutical freeze-drying gives you customized, efficient solutions and innovative, scalable lyophilization equipment for your production. Whether you're installing a new system or upgrading an existing one, Optima Pharma's lyophilizers meet the highest pharmaceutical standards, reducing your time to market and safeguarding your product stability.

An overview of our lyophilization machines

Explore our versatile range of lyophilization and pharmaceutical freeze-drying machines tailored for every application, from new setups to system updates or renovations.

OPTIMA LYO-C Compact and flexible

With its compact design and flexibility, the OPTIMA LYO-C lyophilizer is a versatile solution that fits into various pharmaceutical setups. It lets you make the best use of the space available, without sacrificing performance.

Plate surface:
1–10 m² 
Ice capacity:
10–200 kg
Lyophilization machine
OPTIMA LYO-C Compact and flexible

With its compact design and flexibility, the OPTIMA LYO-C lyophilizer is a versatile solution that fits into various pharmaceutical setups. It lets you make the best use of the space available, without sacrificing performance.

Plate surface:
1–10 m² 
Ice capacity:
10–200 kg
Lyophilization machine
OPTIMA LYO-CS Efficiency in small-batch lyophilization

Designed for small to medium batch sizes, the OPTIMA LYO-CS is a flexible and cost-effective lyophilizer that is perfect for processing pharmaceutical products in the development stages.

Plate surface:
5–20 m² 
Ice capacity:
100–600 kg 
Lyophilization machine
OPTIMA LYO-CS Efficiency in small-batch lyophilization

Designed for small to medium batch sizes, the OPTIMA LYO-CS is a flexible and cost-effective lyophilizer that is perfect for processing pharmaceutical products in the development stages.

Plate surface:
5–20 m² 
Ice capacity:
100–600 kg 
Lyophilization machine
OPTIMA LYO-S High-performance pharmaceutical freeze-drying

The OPTIMA LYO-S is our high-capacity lyophilizer. This pharmaceutical freeze-dryer excels in handling large volumes, ensuring safe and reliable lyophilization for pharmaceutical blockbusters. The chamber is designed as a stand-alone unit, with the intermediate valve as a separate component. The LYO-S can be loaded manually or automatically.

Plate surface:
5–40 m² 
Ice capacity:
100–800 kg 
Lyophilization machine
OPTIMA LYO-S High-performance pharmaceutical freeze-drying

The OPTIMA LYO-S is our high-capacity lyophilizer. This pharmaceutical freeze-dryer excels in handling large volumes, ensuring safe and reliable lyophilization for pharmaceutical blockbusters. The chamber is designed as a stand-alone unit, with the intermediate valve as a separate component. The LYO-S can be loaded manually or automatically.

Plate surface:
5–40 m² 
Ice capacity:
100–800 kg 
Lyophilization machine
OPTIMA LYO-D High performance in a small package

If you need effective lyophilization but space is at a premium, the OPTIMA LYO-D is the solution for you. Its innovative two-level design separates the clean room and machine functions, and makes it easy to integrate into existing pharmaceutical production environments. In addition, a service door that can be fitted on the side makes life easier for your operating personnel.

Plate surface:
5–40 m² 
Ice capacity:
100–800 kg 
Lyophilization machine
OPTIMA LYO-D High performance in a small package

If you need effective lyophilization but space is at a premium, the OPTIMA LYO-D is the solution for you. Its innovative two-level design separates the clean room and machine functions, and makes it easy to integrate into existing pharmaceutical production environments. In addition, a service door that can be fitted on the side makes life easier for your operating personnel.

Plate surface:
5–40 m² 
Ice capacity:
100–800 kg 
Lyophilization machine
OPTIMA pharma | Experts for lyophilization
Team Lyophilization
OPTIMA pharma | Experts for lyophilization
+49 6462 91576 - 0 customer.info@optima-packaging.comWrite e-mail
OPTIMA pharma | Experts for lyophilization
OPTIMA pharma | Experts for lyophilization
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Comparison of all systems

Key Facts
Download freeze-drying product data sheet
OPTIMA Pharma integrated freeze-dryers at work
Sustainable, innovative solutions:
Tailored loading and unloading systems for lyophilizers

Our loading and unloading systems for pharmaceutical freeze-dryers are designed to meet your unique production requirements. From manual loading systems to advanced robotic solutions, they make your lyophilization processes more efficient and reliable.

loading vials into a lyophilizator
Universal loading and unloading: the row-by-row system

This systematic method for handling lyophilization vials aligns them in rows for precision and can be used in various pharmaceutical applications. The system feeds a certain number of objects into the infeed, depending on the shelf width and object dimensions. It then assembles them in rows and pushes them into the lyophilizer. After lyophilization, the objects are unloaded row by row and transferred to the downstream machines.

Loading trolley for freeze drying
Frame loading for special applications

Frame loading organizes vials into separate loads placed into frames for precise lyophilization. Our aim here was to develop a versatile solution that could be used in various industries. It is ideal for small batch sizes, specific primary packaging materials, or as a potential retrofit to your existing system. Once the lyophilization process is complete, the frames are unloaded and removed before the vials are fed into the downstream machines. 

Heavy duty crane transporting a machine in a hallHeavy duty crane transporting a machine in a hall
Freeze-drying in the overall concept for turnkey projects in the pharmaceutical and biotech industries

Lyophilization technology plays a pivotal role in the pharma and biotech sectors. As the home of turnkey, we at Optima develop precisely tailored solutions that encompass the entire project lifecycle, from initial design to full-scale production. They reduce the time it takes to go from concept to market. Thanks to our expertise, we can deliver efficient, scalable and compliant processes that respond to your specific needs in the pharmaceutical and biotechnology industries.

Turnkey solutions / CSPE
Everything you need to know about freeze-drying with OPTIMA Pharma – in 285 seconds
Freeze-drying hands-on
Typical applications for lyophilizers in the pharmaceutical and biotech industries

Biotech

Optima Pharma's advanced lyophilization equipment plays a pivotal role in the biotech sector. These tailored solutions cater to the specific requirements of all kinds of intricate biotechnological products. Thanks to their effective technology, our lyophilizers make processes more efficient while preserving the integrity of sensitive substances.

Doctor drawing up syringe
People in a laboratory

Highly-potent active ingredients

Highly potent active ingredients pose tricky challenges on fill & finish technology, the right containment solution and the Optima's lyophilization solutions.  With comprehensive advice, design and implementation from a single source, we work with you to find the best solution for your requirements.

Peptides & oligonucleotides

Demand for peptides and oligonucleotides in biopharmaceuticals is rising. Optima Pharma is responding with integrated lyophilizers that convert these substances into stable, solid forms. This allows them to be stored and transported safely, while maintaining their efficacy.

woman holding a molecule model
People in a laboratory with tablet and microscope

Viral vectors

Optima specializes in developing bespoke lyophilization cycles for viral vectors used in gene therapy. By reliably preserving them at optimal conditions, they enhance the  stability and longevity of these complex biological products without the need for ultra-low temperature storage.

Blood plasma

Optima Pharma's lyophilization equipment has developed a reputation for reliability in the blood plasma sector, and is trusted by a majority of processing firms worldwide. It delivers unparalleled process control, minimal product loss and consistent aseptic conditions.

Blood plasma: doctor treats patient
laboratory employee with test tray

Lyophilized beads

Lyophilized beads are designed for assays and point-of-care testing, and play a crucial role in diagnostics. Optima's innovative approach to pharmaceutical freeze-drying can help here too, where our precise lyophilization process ensures accuracy and reliability in diagnostic applications.

Diagnostics

Diagnostics in both human and veterinary medicine has highly nuanced needs. Optima Pharma's lyophilization equipment responds to these special requirements, both in production and critical research in life sciences. 

Laboratory employees at a microscope
Success stories from the world of freeze-drying
OPTIMA pharma | Experts for lyophilization
Do you have questions or would you like to discuss your specific requirements with an Optima Pharma expert?
OPTIMA pharma | Experts for lyophilization
OPTIMA pharma | Experts for lyophilization
OPTIMA pharma | Experts for lyophilization
+49 6462 91576 - 0 Write e-mail
Jörg Rosenbaum, Jakob-Trenk
Team Lyophilization
OPTIMA pharma | Experts for lyophilization
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